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| User's Agreement: Use of this site is available free of charge to all academic entities. Please reference any use of information or images from this site. Commercial entities must obtain prior licensing authorization before usage. Contact us to obtain licensing authorization. Publications: Liu, B.A., Jablonowski, K., Raina, M., Arcé, M., Pawson, T., and Nash, P.D. (2006) The Human and Mouse Complement of SH2 Domain Proteins - establishing the boundaries of phosphotyrosine signaling. Molecular Cell 22: 851-868. Journal - Article pdf - Supplementary data - PubMed Statistics: The current build of this site is dated June 16, 2006 The site now contains information pertaining to: 110 human proteins with SH2 110 mouse proteins with SH2 121 SH2 domains 168 SH2 structures 37 SH2 proteins have at least one structure 33 diseases associated with SH2 genes 21 SH2 proteins associated with diseases 94 mouse knock-outs have been made against SH2 genes 80 genes encoding SH2 proteins have mouse knock-outs Acknowledgements: The bioinformatic analysis of the SH2 domains is a collaborative project involving the following groups:
This site was created with considerable help from Conrad Lee for web and flash programming, Bernard Liu for research and table creation, Eshana Shah for structural and schematic images, and Ramon Valladolid for server set-up and maintenance. The research aspect of this page is reflected in the forthcoming publication of the Bioinformatic Analysis of the Human and Mouse complement of SH2 domains. This site is maintained by the Nash lab at The University of Chicago with assistance from the computer group staff at The Ben May Institute for Cancer Research. Contact Us:
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